Other medicines & supplements

Several people said prescribed propranolol, a beta blocker, helped a lot, some noticing it from the start. Others combined it with diet changes or with Allegra, Sudafed and Pepcid, and one felt the diet did most of the work. It's a prescription drug — personal reports only, so talk to a doctor first.

A few people said drinking heated hemp (CBD) tea before orgasm worked well for them; some said it worked far better than other things they'd tried, and one said it cleared their symptoms and they plan to stick with it.

Several people said taurine helped: one took about 2–3 g a day, another needed to take it several times a day for some days before it seemed to work, and a third had two ejaculations in one day and felt fine. Two others said it did nothing for them, one at a 2 g dose. Personal reports — check with a doctor before taking supplements.

Accounts were mixed. One person said CBD has worked long-term, even with an orgasm every day, and another put a little CBD oil under the tongue right after and felt a bit calmer. A third said hemp tea does nothing if you drink it after the orgasm.

Two people described vaping CBD around or after orgasm. One felt CBD and POIS were fighting with no clear winner but noticed symptoms lasting a shorter time; the other said vaping CBD flower gets them close to 100%. Feedback is very limited.

Two people said psychiatric medication eased things a little: one on sertraline (Zoloft) plus other drugs still had symptoms but milder, and no more wet dreams; another on citalopram with perphenazine found it helped a bit. But someone else tried two SSRIs with no luck — their anxiety shot up and they were shaking every day. Personal reports only — these are prescription drugs that need a doctor's guidance.

Two people said taking selenium, zinc and ZMA (a zinc, magnesium and vitamin B6 blend) after orgasm made a noticeable difference, though they didn't say what improved. One took 3 capsules of zinc (about 25 mg in total) and 1 capsule of selenium right after orgasm. Personal reports only — check with a doctor before taking supplements.

Two people did different things: one took an antihistamine before bed on nights they thought a wet dream might happen, while the other has mostly avoided them in recent years by staying up as long as needed, sometimes all night — at great cost, but worth it to avoid being debilitated by POIS. Personal reports — talk to a doctor before using medication.

Two people said their symptoms eased after supplementing with vitamin D. One took a high dose every day for at least a year to cut down on wet dreams, without saying the exact dose. Personal reports — check with a doctor before taking supplements.

One person said they avoid digestive enzyme supplements containing ox bile or protease because they believe these cause histamine release in their gut. The post didn't say what symptoms they had.

One person said drinking strong Korean ginger tea regularly worked really well for them, without saying which symptoms improved or how much they drank.

One person said probiotics helped a bit, without saying which kind, how much, or what improved. Personal report only — check with a doctor before taking supplements.

One person said that when they wake up after a wet dream, they apply magnesium oil all over their body. They found it helpful, though they didn't say which symptoms improved.

One person mentioned taking ibuprofen after waking from a nocturnal emission to try to ease their symptoms. The only quote kept is “maybe coffee”, which doesn't match, so details are thin and the result is unclear. Personal report only — check with a doctor before using medication.

One person said that after more than a year on estrogen hormone replacement therapy their night emissions stopped and the urge to masturbate became much easier to resist. The report is about fewer emissions and less libido, not about post-ejaculation symptoms directly. Personal report only — talk to a doctor before any hormone treatment.

One person said eating protein after a wet dream, maybe along with coffee, helped, without saying how much or what exactly improved.

One person said that getting drunk before orgasm reduced their POIS symptoms by up to 95%, but only with clear, gluten-free liquor. It's a single report and no one else weighed in; drinking carries its own risks, so this isn't a recommendation.

One person said the only thing that somewhat works for them is a wide range of antihistamines combined with NSAID painkillers and benzodiazepines. No drug names, doses or timing were given. Personal report only — combining these medicines carries risks, so talk to a doctor first.

One person said their symptoms eased after a few weeks of taking bromocriptine every day. No dose was given and no one else reported back. It's a prescription drug and this is a personal report — talk to a doctor before using it.

One person listed the medicines they're on: Zoloft and lorazepam for serotonin and GABA, plus bromocriptine to lower prolactin and boost dopamine. The comment mostly lists drugs and doesn't spell out what bromocriptine itself did. These are prescription drugs and this is a personal report — talk to a doctor before using them.

One person said Butea Superba extract with bioperine has helped them the most of everything they tried, without saying which symptoms improved. No one else reported on it. Personal report only — check with a doctor before taking supplements.

One person said caffeine helps their symptoms, but only if they stay relaxed; otherwise it makes their anxiety worse. It's the only report so far.

One person said using cannabis before orgasm had helped their symptoms in the past. They didn't say how much, how they used it, or how far ahead.

One person said they vape or eat CBD/THC cannabis products at least once a day, find it really helps, stay sober enough to be productive, and end up taking fewer pills. They didn't say which symptoms improved. Personal report only; cannabis is restricted in many places, so talk to a doctor first.