Muscles & pain

Three people said zinc helped: one felt something change and felt more driven on daily zinc capsules, one said zinc plus selenium raised their testosterone by 8 nmol, and one said that, tried several times, it prevented weak muscles and sore knees — though they allowed it could be placebo. High doses of zinc can cause nausea; check with a doctor before supplementing.

Three people said a stretch without orgasm helped: one avoided ejaculating for six weeks before a fight and felt release weakens the knees and legs; one said after at least a week without any orgasm they have no slow reflexes, brain fog or sluggish movement; and one needs about three weeks with no wet dreams to feel full relief from brain fog.

Two people said POIS symptoms eased a good deal after impacted wisdom teeth were removed. One had all four out; those teeth used to hurt during POIS, and symptoms improved but didn't vanish. The other said the tooth problem virtually disappeared and POIS symptoms dropped significantly. Tooth removal is a medical procedure, so ask a dentist.

Two people mentioned CBD oil. One used a whole stack of supplements including CBD and said symptoms dropped by about 80%, with episodes shrinking from 5 days to 24–36 hours. The other used large amounts as needed, under the tongue or vaped, reportedly for pain.

Two people said taking ibuprofen and Claritin (loratadine, an allergy pill) together right after ejaculation eased their pain and allergy-like reaction, and one called the combination good relief. Neither gave doses. Personal reports — talk to a doctor before using medication.

Two people with muscle twitching and similar symptoms said things eased after they stopped masturbating: one felt huge relief after having feared it was ALS, and another said odd symptoms that appeared during a reboot gradually faded.

Two people said vitamin D helped: one took 10,000 IU along with a better diet and said they were close to 100% better; another said they used to get muscle cramps every night when lying down to sleep, but not anymore. One also paired it with vitamin K2. 10,000 IU is a high dose — personal reports only, check with a doctor before taking it.

Two people said these helped: one took a single high dose of zinc (50–75 mg) now and then and felt weak muscles and sore knees after orgasm eased, but stressed they don't take it often and that nobody should, since too much can be unhealthy over time; the other, who has high prolactin, takes bromocriptine and said it helps with body weakness from POIS. Personal reports — check with a doctor before using medication or supplements.

Two people said it helped: one managed a month without ejaculating and felt absolutely amazing, and another said the best thing for them was cutting out porn and masturbation for 3–6 months, then returning slowly. The details differ between reports and are fairly vague.

Two people mentioned things that helped: one said running through the muscle weakness in their back and legs clears it out, and another mentioned taking vitamin B12 by mouth without further detail. Personal reports — talk to a doctor before taking supplements.

Three people talked about zinc: two found it helped counter weak legs and muscle weakness (one linked the weakness to prolactin), while a third tried a high dose and got big red marks on the skin of their back. Personal reports — check with a doctor before taking supplements.

One person said that after about 3.5 months without ejaculating, muscle mass slowly comes back, especially when combined with a keto or carnivore diet.

One person dealing with joint pain after orgasm said they use black seed oil together with Celebrex, an antihistamine (regular Allegra) and holy basil, and that it helps. They did not say how much the oil alone contributed.

One person said that for joint pain after orgasm they take Celebrex plus antihistamines (regular Allegra, black seed oil and holy basil) and found it helped. Holy basil was just one part of that mix, and no dose was given. Personal report only — check with a doctor before combining medication and herbal supplements.

On losing muscle mass, one person said it slowly comes back after about 3.5 months of abstinence, especially alongside a keto or carnivore diet. This is the only report so far.

For POIS-related pain, one person said they vape or eat cannabis as needed (also for fun). No product type or amount was given.

One person who got joint pain after orgasm said they took Celebrex (celecoxib) together with an antihistamine (regular Allegra), black seed oil and holy basil, and felt it helped. No dose or timing was given.

One person said 12-hour fexofenadine (Allegra), an allergy medicine, eased their aches and pains but left them feeling a bit out of it. Personal report — talk to a doctor before using medication.

One person said ibuprofen helps more with the physical side of an episode, such as tension, a stiff neck and a runny nose. No dose was given. Personal report only — talk to a doctor before using medication.

One person said they took one ibuprofen two hours before orgasm and coped better, but they were also doing other things and could not tell which one helped. A single personal report — talk to a doctor before using medication.

In reply to another poster, one person said the symptoms described go away with seed saving and avoiding ejaculation, and that building the discipline to keep up nofap is better. No duration was given and no one else reported on it.

One user said they sometimes use celecoxib during a POIS episode to ease aches and pains, though they worry that NSAIDs hurt diamine oxidase (DAO). Personal report only — talk to a doctor before using medication.

One person said pre-cum triggers extreme leg pain and lower back pain, and NSAIDs such as meloxicam, Arcoxia (etoricoxib) or Celebrex (celecoxib) help. No dose or timing was given. Personal report — these are prescription anti-inflammatory drugs, so talk to a doctor first.

One person said taking 2 g of curcumin a day helped a lot with their joint pain and brain fog, though it gave them stomach trouble. Personal report only — check with a doctor before taking supplements.